Affinity 2007 Conference
NYU Kimmel Center, New York, NY
July 8 - 12, 2007

Sponsors

The organizers of Affinity 2007 are particularly grateful for the support of our Sponsors. Their active participation and contributions throughout the years have been invaluable to the continual success of our meeting.

GWC Technologies (www.gwctechnologies.com) - First time and future sponsor
"GWC Technologies: your partner in label-free array analysis and biosensor development"

We are pleased to announce that Voula Kodoyianni will be representing GWC with a poster entitled:

A Flexible Easy to use Platform for Analyzing Molecular Interactions on Arrays

Pierce (ThermoFisher) - Long time sponsor and host to the Pierce Affinity Award

The 2005 winner of the Pierce Award in Affinity Technology was Bertrand Seraphin of the CNRS, inventor of the widely-used Tandem Affinity Purification (TAP) technology and founder of Cellzome.

Recipients since inception of award are: Klaus Mosbach (1985), Meir Wilchek (1987), Chris Lowe (1989), Irwin Chaiken (1991), Jerker Porath (1993), Mathias Uhlen/Fred Regnier (1995), Shin Ishii (1997), Mookambeswaran (Viji) Vijayalakshmi (1999), Stellan Hjertan (2001).

Nominations for the Pierce Affinity 2007 Award are now closed. The Pierce Affinity Award Committee members for Affinity 2007 are: Meir Wilchek, Ed Bayer and Gidi Fleminger. Special thanks to Krishna Mallia and Peter Bell (Pierce/ThermoFisher) for making this award possible.

Pall Life Sciences - Sponsorship given to encourage student participation.
"Pall Life Sciences - New Science. New Thinking."

Sanofi pasteur - Long time sponsor
"Sanofi pasteur - the vaccines business of Sanofi Aventis Group"

Hoffmann - La Roche - Long time sponsor and host to Roche Younger Investigators Award

Student participation is a great tradition of the ISMR Affinity Conferences. One aspect of this tradition is the Roche-Sponsored Younger Investigator Award. All students presenting their work will be automatically considered for these awards. Abstracts received before April 1st, 2007 will be reviewed and considered for short oral presentations. Prizes will be awarded to Younger Investigators selected from both poster and oral presentations.

Molecular Imprinted Polymers for Selective Protein Adsorption by Miniemulsion Polymerization
Marc Herold, Klaus Niedergall, Melanie Dettling, Yunxiao Wang, Guenter Tovar
Fraunhofer-Institute for Interfacial Engineering and Biotechnology & Institute for Interfacial Engineering, University of Stuttgart, Stuttgart, Germany

A Potentiometric Biosensor Built with Surface Molecular Imprinting Technology
Yantian Wang (1), Zhiquan Zhang (2), Vijay Jain (3), Jinju Yi (4), Steffen Mueller (5),  Jonathan Sokolov (1), Basil Rigas (2), Kalle Levon (6), Miriam H. Rafailovich (1*)
1. Department of Materials Science and Engineering, Stony Brook University, NY, 2.  Department of Medicine, Stony Brook University, NY, 3.  Herricks High School, New Hyde Park, NY, 4.  Old-Bethpage John, F. Kennedy High School, Plainview, NY, 5.  Department of Molecular Genetics and Microbiology, Stony Brook University, NY, 6.  Department of Chemical and Biological Science and Engineering, Polytechnic University, Brooklyn, NY

Conformational Flexibility and Kinetic Complexity in Antigen-antibody Interactions
Katerina Kourentzi, Mohan Srinivasan, Sandra J. Smith-Gill and Richard C. Willson
Department of Chemical and Biomolecular Engineering, University of Houston, Houston, TX USA

Shape Selectivity versus Functional Group Pre-organization in Molecularly Imprinted Polymers
Melissa Collins and David Spivak
Department of Chemistry, Lousiana State University, Baton Rouge, LA USA

Engineered 5S Ribosomal RNAs displaying Anti-VEGF and Malachite Green Aptamers
Xing Zhang (1), Ajish S. R. Potty (2), George W. Jackson (2), George E. Fox (1), and Richard C. Willson (1, 2)
1.  Department of Biology and Biochemistry, 2.  Department of Chemical Engineering, University of Houston, Houston, TX USA

Magnetic Biosensor Diagnostic Technology
Divya Namuduri (1,5), Binh Vu (3,5), Jennifer Knoop (3,5), Vishal Parekh (2,5), Darren Smith (2,5), Ariel Ruiz (2,5), James Rantschler (2,5), Paul Ruchhoeft (2,5), Richard C. Willson (3,4,5), Dmitri Litvinov (1,2,3,5)
1. Materials Engineering, 2. Electrical & Computer Engineering, 3. Chemical and Biomolecular Engineering, 4. Biology and Biochemistry, 5. Center for Nanomagnetic Systems, University of Houston, Houston,TX USA

Synthetic Affinity Ligands to Bind Cutinase in an Active and Stable Conformation
Isabel T. de Sousa (1), Luisella Ruiu (1,2), Chistopher R. Lowe (2), M. Angela Taipa (1)
1. IBB-Institute for Biotechnology and Bioengineering, Centro de Engenharia Biologica e Quimica, Instituto Superior Tecnico, Lisboa, Portugal, 2. Institute of Biotechnology, University of Cambridge, Cambridge UK

Preliminary Stability Studies of Cutinase Immobilised onto Synthetic Affinity Ligands
L. Ruiu (1,2), I.T. Sousa (1), A.C.A. Roque (1,2), C.R. Lowe (2), M.A. Taipa (1)
1.  IBB-Institute for Biotechnology and Bioengineering, Centro de Engenharia Biológica e Química, Instituto Superior Técnico, Lisboa, Portugal, 2.  Institute of Biotechnology, University of Cambridge, Cambridge UK

Molecular Study of Autoantibody Rheumatoid Factor using Pseudo Bioaffinity Hollow Fiber Membrane Chromatography
A.S. Kamalanathan (1), Tatu. U (2), M.A.Vijayalakshmi (1)
1. Center for Bioseparation Technology, VIT University, Vellore, India, 2. Department of Biochemistry, Indian Institute of Technology, Bangalore, India

Detection of Immunological Interactions via the Magnetic Acoustic Resonator Sensor
Kioupritzi E., Stevenson and Lowe, C.R
Institute of Biotechnology, University of Cambridge, Cambridge UK

Development of HIC Media Useful for Isolation of Proteins Carrying Single Amino Acid Substitutions
Kristian Becker*, Elisabeth Hallgren**, Enrique Carredano**, Ronnie Palmgren** and Leif Balow**
*Department of Pure and Applied Biochemistry, Centre for Chemistry and Chemical Engineering, Lund University Lund, Sweden **GE Healthcare Bio-Sciences AB, Uppsala, Sweden.

Development of New OMNiMIPs (One Monomer Molecularly Imprinted Polymers)
Jason LeJeune and David Spivak
Department of Chemistry, Lousiana State University, Baton Rouge, LA USA

Effects of Gold Nanoparticles on PCR Amplicon Size
Binh Vu, Dmitri Litvinov, Richard Willson
University of Houston, Houston, TX USA

Retro-reflectors for Immunoassays and Biosensors
Steven M. Kemper (1), Tim Sherlock (2), Kaajal D. Shah (3), Eliedonna Cacao (1), Paul Ruchhoeft (2), Robert L. Atmar (4), Richard C. Willson (1,3)
1. University of Houston (UH) Department of Chemical and Biomolecular Engineering, 2. UH Department of Electrical and Computer Engineering, 3. UH Department of Biology and Biochemistry, 4. Baylor College of Medicine, Houston, TX USA

Novel Affinity Ligands for the Purification of Antibody Fragments
Jonathan M. Haigh, Christopher R. Lowe
Institute of Biotechnology, University of Cambridge, Cambridge, UK

Biophysical Characterization of Aptamer-Protein Interactions
Ajish S. R. Potty (1), Katerina Kourentzi (1), Han Fang (2), George W. Jackson (1?), Peter Schuck (3), Dar-Chone Chow (2), Glen Legge (4), and Richard C. Willson (1,4*)
(1) Department of Chemical and Biomolecular Engineering, University of Houston, TX 77204-4004, USA, (2) Department of Chemistry, University of Houston, Houston, TX, USA, (3) Division of Bioengineering and Physical Science, National Institute of Health, Bethesda, MD USA, (4) Department of Biology and Biochemistry, University of Houston, Houston, TX USA, (?) Present address: BioTex, Inc., Houston, TX USA

Enhanced Protein Affinity and Selectivity of Clustered-charge Anion Exchange Adsorbents
Joseph Y. Fu (1) , Sindhu Balan (2), Ajish Potty (3), Van Nguyen (2) and Richard C. Willson (1, 2, 3)*
(
1) Biomedical Engineering Program, (2) Department of Biology and Biochemistry, (3) Department of Chemical and Biomolecular Engineering, University of Houston, Houston, TX

Roche Younger Investigator Award Committee
Ana Cecília Roque, Chair - Universidade Nova de Lisboa, Portugal
Richard Willson - University of Houston, TX USA

Lars Hagel - GE Healthcare, Uppsala, Sweden
Irwin Chaiken, Drexel University, PA USA
George Ehrlich, Hoffmann - La Roche, NJ USA
Pascal Bailon (ret.), Hoffmann - La Roche, NJ USA

At the 2005 meeting, the recipients of the awards were:

Pictured from left to right: A. Hussain, E. Kiuprizi, G. Ramos-Clamont, C. Roque, R. Johansson, B. Araya, R. Willson, G. Ehrlich, K. Kuerzinger and L. Hagel. Photo courtesy of Konrad Kuerzinger, Roche Penzberg

Reine Johansson (Sten Ohlson, U. Kalmar, Sweden) - Weak Affinity Chromatography using Carbohydrate Binding Modules
Gabriela Ramos-Clamont (Luz Vasquez-Moreno, CIAD, Sonora, Mexico) - E. coli K88 Interaction with Serum Porcine IgA Oligosaccharides
Abid Hussain (Chris Lowe, U. Cambridge, UK) - Synthesis of Carbohydrate Receptors
Bernaditta Araya, Cecilia Roque and Eleftheria Kiuprizi (Chris Lowe, U. Cambridge, UK) - Magnetic Acoustic Resonator Sensors

GE Healthcare (formerly Amersham/Pharmacia Biosciences) - Long time sponsor and host to Jerker Porath Award at Affinity 2005, Uppsala, Sweden

The recipient of this one time award was Mathias Uhlen, Professor of Biotechnology at the Royal Institute of Technology (KTH), Stockholm, Sweden.

Pictured above are Jerker and Mathias. Photo courtesy of Jan-Christer Janson, Uppsala University

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